Absorptive clearance of DTPA as an aerosol-based biomarker in the cystic fibrosis airway.

Abstract

Biomarkers providing in vivo quantification of the basic elements of cystic fibrosis (CF) lung disease are needed. A study was performed to determine whether the absorption of a small radiolabelled hydrophilic molecule (Indium-111 (In-)DTPA) would be increased in CF airways. DTPA clearance has been used previously to assess epithelial permeability and may… (More)
DOI: 10.1183/09031936.00059009

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