Absorption of solute from the solutions. 2. Repression of adsorption of cyanocobalamin on talc by polyvinylpyrrolidone.

@article{Moriguchi1969AbsorptionOS,
  title={Absorption of solute from the solutions. 2. Repression of adsorption of cyanocobalamin on talc by polyvinylpyrrolidone.},
  author={Ikuo Moriguchi and Nobuyoshi Kaneniwa},
  journal={Chemical \& pharmaceutical bulletin},
  year={1969},
  volume={17 5},
  pages={
          961-5
        }
}
The adsorption of cyanocobalamin on talc was remarkably repressed by polyvinylpyrrolidone. An investigation utilizing equilibrium dialysis revealed that the repression by PVP was caused by adsorption of PVP on talc and not by any direct interaction between PVP and cyanocobalamin. Adsorption of PVP on talc was endothermic and the value of the apparent entropy change was positive. PVP and cyanocobalamin adsorbed on talc with obedience to the Langmuir isotherm equation. But the data of adsorption… 
2 Citations
Adsorption of benzoic acid on sulphadimidine: suppressive effect of some hydrophilic polymers
TLDR
Dialysis experiments revealed that, within the range of concentrations used, neither PVP nor methylcellulose was significantly bound to benzoic acid.
Pharmaceutical sciences--1970: literature review of pharmaceutics.
This review of the literature represents a comprehensive cross section of the research and development efforts in various selected disciplines of the pharmaceutical sciences. It is the ninth annual