Absorption of cholesterol by the gallbladder.


To study whether cholesterol is absorbed by the gallbladder, we instilled from 1 to 300 nmoles of [4-14C]cholesterol dissolved in 1 ml of guinea pig bile into the in situ guinea pig gallbladder. The bile used in these experiments contained 7 mumole/ml bile acid, 27 nmole/ml lecithin, and 8 nmol/ml cholesterol. To this bile, we added the radioactive… (More)

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