Absorption of N-phenylpropenoyl-L-amino acids in healthy humans by oral administration of cocoa (Theobroma cacao).

@article{Stark2008AbsorptionON,
  title={Absorption of N-phenylpropenoyl-L-amino acids in healthy humans by oral administration of cocoa (Theobroma cacao).},
  author={Timo D. Stark and Roman Lang and Daniela Barbara Keller and Andreas Hensel and Thomas Hofmann},
  journal={Molecular nutrition & food research},
  year={2008},
  volume={52 10},
  pages={1201-14}
}
Besides flavan-3-ols, a family of N-phenylpropenoyl-L-amino acids (NPAs) has been recently identified as polyphenol/amino acid conjugates in the seeds of Theobroma cacao as well as in a variety of herbal drugs. Stimulated by reports on their biological activity, the purpose of this study was to investigate if these amides are absorbed by healthy volunteers after administration of a cocoa drink. For the first time, 12 NPAs were quantified in human urine by means of a stable isotope dilution… CONTINUE READING

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