Absorption kinetics of insulin after subcutaneous administration.

  title={Absorption kinetics of insulin after subcutaneous administration.},
  author={Tue S\oeborg and Christian Hove Rasmussen and Erik Mosekilde and Morten Colding-J\orgensen},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  volume={36 1},
Many diabetic patients depend on regular and well-controlled administration of insulin to avoid unacceptable excursions in plasma glucose. A complicating factor is that the absorption of insulin shows a considerable variability, both between patients, and from administration to administration for the same patient. To understand the mechanisms that influence this variability we present a quantitative description of the absorption kinetics for both soluble insulin and insulin crystals. The… CONTINUE READING