Absorption kinetics and action profiles of subcutaneously administered insulin analogues (AspB9GluB27, AspB10, AspB28) in healthy subjects.

@article{Kang1991AbsorptionKA,
  title={Absorption kinetics and action profiles of subcutaneously administered insulin analogues (AspB9GluB27, AspB10, AspB28) in healthy subjects.},
  author={S W Kang and Jens Brange and Anna Burch and Aage V\olund and David R. Owens},
  journal={Diabetes care},
  year={1991},
  volume={14 11},
  pages={1057-65}
}
OBJECTIVE The subcutaneous absorption and resulting changes in plasma insulin or analogue, glucose, C-peptide, and blood intermediary metabolite concentrations after subcutaneous bolus injection of three soluble human insulin analogues (AspB9GluB27, monomeric; AspB28, mixture of monomers and dimers; and AspB10, dimeric) and soluble human insulin were evaluated. RESEARCH DESIGN AND METHODS Fasting healthy male volunteers (n = 7) were studied on five occasions 1 wk apart randomly receiving 0.6… CONTINUE READING

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