Absorption dynamics of organic chemical transport across trout gills as related to octanol-water partition coefficient.

@article{McKim1985AbsorptionDO,
  title={Absorption dynamics of organic chemical transport across trout gills as related to octanol-water partition coefficient.},
  author={James McKim and Peter Schmieder and Gerhard Veith},
  journal={Toxicology and applied pharmacology},
  year={1985},
  volume={77 1},
  pages={1-10}
}
An in vivo fish preparation was used that allowed a direct measure of the transport rates of 14 different organic chemicals across the gills of rainbow trout (Salmo gairdneri). The chemicals, all C14 labeled, were selected from five classes, encompassing a range of octanol-water partition coefficient (log P) values, from 0.23 (ethyl formate) to 7.5 (mirex). The uptake efficiency (extraction efficiency) of each chemical was determined by monitoring the inspired and expired water of trout exposed… CONTINUE READING

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