Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.

  title={Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.},
  author={Herman Baker and Oscar Frank},
  journal={Journal of nutritional science and vitaminology},
  volume={22 SUPPL},
  • H. BakerO. Frank
  • Published 1 August 1976
  • Medicine
  • Journal of nutritional science and vitaminology
Oral administration of lipid-soluble allithiamines [thiamine propyl disulfide (TPD) and thiamine tetrahydrofurfuryl disulfide (TTHF)] rapidly increased thiamine activity in whole blood, red blood cells, cerebrospinal fluid, and urine in normal and thiamine-deficient subjects. These thiamine congeners also restored red blood cell transketolase to normal in alcoholics with thiamine deficiency. Such repletion equaled that produced by parenteral, water-soluble thiamine hydrochloride (THCl) or… 

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