Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.
@article{Baker1976AbsorptionUA, title={Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.}, author={H. Baker and O. Frank}, journal={Journal of nutritional science and vitaminology}, year={1976}, volume={22 SUPPL}, pages={ 63-8 } }
Oral administration of lipid-soluble allithiamines [thiamine propyl disulfide (TPD) and thiamine tetrahydrofurfuryl disulfide (TTHF)] rapidly increased thiamine activity in whole blood, red blood cells, cerebrospinal fluid, and urine in normal and thiamine-deficient subjects. These thiamine congeners also restored red blood cell transketolase to normal in alcoholics with thiamine deficiency. Such repletion equaled that produced by parenteral, water-soluble thiamine hydrochloride (THCl) or… CONTINUE READING
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References
SHOWING 1-10 OF 13 REFERENCES
Am. J. Clin. Nutr
- Am. J. Clin. Nutr
- 1974
Clin. Sci
- Clin. Sci
- 1972
Physiol. Rev
- Physiol. Rev
- 1972
Am. J. Clin. Nutr
- Am. J. Clin. Nutr
- 1971
Am. J. Clin. Nutr
- Am. J. Clin. Nutr
- 1970
J. Lab. Clin.Med
- J. Lab. Clin.Med
- 1970
Am. J. Clin. Nutr
- Am. J. Clin. Nutr
- 1968
J. Lab. Clin. Med
- J. Lab. Clin. Med
- 1968
Ciba Foundation Symposium, Little, Brown and Co
- Ciba Foundation Symposium, Little, Brown and Co
- 1967