• DOI:10.3177/JNSV.22.SUPPLEMENT_63
Corpus ID: 18816575

Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.

@article{Baker1976AbsorptionUA,
  title={Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.},
  author={H. Baker and O. Frank},
  journal={Journal of nutritional science and vitaminology},
  year={1976},
  volume={22 SUPPL},
  pages={
          63-8
        }
}

• H. Baker, O. Frank
• Published 1976
• Chemistry, Medicine
• Journal of nutritional science and vitaminology

Oral administration of lipid-soluble allithiamines [thiamine propyl disulfide (TPD) and thiamine tetrahydrofurfuryl disulfide (TTHF)] rapidly increased thiamine activity in whole blood, red blood cells, cerebrospinal fluid, and urine in normal and thiamine-deficient subjects. These thiamine congeners also restored red blood cell transketolase to normal in alcoholics with thiamine deficiency. Such repletion equaled that produced by parenteral, water-soluble thiamine hydrochloride (THCl) or… Expand