Absorption, distribution, metabolism and excretion of [14C]dexlansoprazole in healthy male subjects.

@article{Grabowski2012AbsorptionDM,
  title={Absorption, distribution, metabolism and excretion of [14C]dexlansoprazole in healthy male subjects.},
  author={Brian A. Grabowski and Ronald D Lee},
  journal={Clinical drug investigation},
  year={2012},
  volume={32 5},
  pages={319-32}
}
BACKGROUND AND OBJECTIVE The proton pump inhibitor dexlansoprazole is a modified-release formulation of dexlansoprazole, an enantiomer of lansoprazole, which employs a Dual Delayed Release™ (DDR) delivery system. This study was conducted in healthy subjects to assess the absorption, distribution, metabolism and excretion of a 60 mg dose of [14C]dexlansoprazole. METHODS After multiple daily doses of dexlansoprazole DDR for 4 days followed by a single dose of [14C]dexlansoprazole on day 5… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…