Absorption, distribution, metabolism, and excretion of decursin and decursinol angelate from Angelica gigas Nakai.

@article{Kim2009AbsorptionDM,
  title={Absorption, distribution, metabolism, and excretion of decursin and decursinol angelate from Angelica gigas Nakai.},
  author={K. M. Kim and Myo-Jeong Kim and J. Kang},
  journal={Journal of microbiology and biotechnology},
  year={2009},
  volume={19 12},
  pages={
          1569-72
        }
}
The pharmacokinetics of decursin and decursinol angelate (D/DA) was investigated in male SD rats following oral and intravenous administration. D/DA and metabolites obtained from in vitro samples were evaluated by LC/MS. The level of D/DA and metabolized decursinol in the blood following oral and intravenous administration declined according to first-order kinetics, with T1/2 values of 56.67, 58.01 and 57.22 h, respectively, being observed after administration of a dose of 2 mg/kg body weight… Expand
22 Citations
Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats
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Effects of Angelica gigas Nakai on the production of decursin- and decursinol angelate-enriched eggs.
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