Absorbing phenomena and escaping time for Muller's ratchet in adaptive landscape

  title={Absorbing phenomena and escaping time for Muller's ratchet in adaptive landscape},
  author={Shuyun Jiao and Ping Ao},
  journal={BMC Systems Biology},
  pages={S10 - S10}
BackgroundThe accumulation of deleterious mutations of a population directly contributes to the fate as to how long the population would exist, a process often described as Muller's ratchet with the absorbing phenomenon. The key to understand this absorbing phenomenon is to characterize the decaying time of the fittest class of the population. Adaptive landscape introduced by Wright, a re-emerging powerful concept in systems biology, is used as a tool to describe biological processes. To our… 
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