Absolute quantitation of iodine-123 epidepride kinetics using single-photon emission tomography: comparison with carbon-11 epidepride and positron emission tomography

@article{Almeida1999AbsoluteQO,
  title={Absolute quantitation of iodine-123 epidepride kinetics using single-photon emission tomography: comparison with carbon-11 epidepride and positron emission tomography},
  author={Pedro Almeida and Maria-Joao Ribeiro and Michel Bottlaender and Christian Loc’h and Oliver Langer and Daniel Strul and P. Hugonnard and Pierre Grangeat and Bernard Mazi{\`e}re and Bernard Bendriem},
  journal={European Journal of Nuclear Medicine},
  year={1999},
  volume={26},
  pages={1580-1588}
}
Epidepride labelled with iodine-123 is a suitable probe for the in vivo imaging of striatal and extrastriatal dopamine D2 receptors using single-photon emission tomography (SPET). Recently, this molecule has also been labelled with carbon-11. The goal of this work was to develop a method allowing the in vivo quantification of radioactivity uptake in baboon brain using SPET and to validate it using positron emission tomography (PET). SPET studies were performed in Papio anubis baboons using 123I… CONTINUE READING