Absolute quantification of cell-free microRNAs in cancer patients


The hypothesis to use microRNAs (miRNAs) circulating in the blood as cancer biomarkers was formulated some years ago based on promising initial results. After some exciting discoveries, however, it became evident that the accurate quantification of cell-free miRNAs was more challenging than expected. Difficulties were linked to the strong impact that many… (More)


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@inproceedings{Ferracin2015AbsoluteQO, title={Absolute quantification of cell-free microRNAs in cancer patients}, author={Manuela Ferracin and Laura Lupini and Irene Salamon and Elena Saccenti and Maria Vittoria Zanzi and Andrea Rocchi and Lucia Da Ros and Barbara Zagatti and Gentian Musa and Cristian Bassi and Alessandra Mangolini and Giorgio Narciso Cavallesco and Antonio Frassoldati and Stefano Volpato and Paolo Carcoforo and Alan B. Hollingsworth and Massimo Negrini}, booktitle={Oncotarget}, year={2015} }