Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy.

@article{Ozdemir2007AbsoluteQO,
  title={Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy.},
  author={Mahir Sinan Ozdemir and Harmen Reyngoudt and Yves De Deene and Hakan S. Sazak and Els Fieremans and Steven Delputte and Yves D'Asseler and Wim Derave and Ignace Lemahieu and Eric Achten},
  journal={Physics in medicine and biology},
  year={2007},
  volume={52 23},
  pages={
          6781-94
        }
}
Carnosine has been shown to be present in the skeletal muscle and in the brain of a variety of animals and humans. Despite the various physiological functions assigned to this metabolite, its exact role remains unclear. It has been suggested that carnosine plays a role in buffering in the intracellular physiological pHi range in skeletal muscle as a result of accepting hydrogen ions released in the development of fatigue during intensive exercise. It is thus postulated that the concentration of… CONTINUE READING

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