Absolute preoperative C-reactive protein predicts metastasis and mortality in the first year following potentially curative nephrectomy for clear cell renal cell carcinoma.

@article{Johnson2010AbsolutePC,
  title={Absolute preoperative C-reactive protein predicts metastasis and mortality in the first year following potentially curative nephrectomy for clear cell renal cell carcinoma.},
  author={Timothy V. Johnson and Ammara Abbasi and Ashli A. Owen-Smith and Andrew N. Young and Kenneth E Ogan and John G. Pattaras and Peter T. Nieh and Fray F. Marshall and Viraj A. Master},
  journal={The Journal of urology},
  year={2010},
  volume={183 2},
  pages={480-5}
}
PURPOSE C-reactive protein is an inflammatory biomarker associated with tumor burden and metastasis in renal cell carcinoma. Recent studies suggest that preoperative C-reactive protein predicts metastasis and mortality after nephrectomy for localized renal cell carcinoma. However, these studies dichotomized C-reactive protein (typically 10 mg/l or greater vs less than 10 mg/l). Considering the continuous range of C-reactive protein (less than 1 mg/l to greater than 100 mg/l) we assessed the… CONTINUE READING

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