Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in brain SPECT

@article{Fakhri2000AbsoluteAQ,
  title={Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in brain SPECT},
  author={George El Fakhri and M. F. Kijewski and S. Moore},
  journal={2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149)},
  year={2000},
  volume={3},
  pages={18/7-1811 vol.3}
}
Estimates of SPECT activity within certain deep brain structures could be useful for clinical tasks such as early prediction of Alzheimer's disease with Tc-99m or Parkinson's disease with I-123; however, such estimates are biased by poor spatial resolution and inaccurate scatter and attenuation corrections. We compared an analytical approach to more accurate quantitation (AA) to a slower iterative approach (IA). Monte Carlo simulated projections of 12 normal and 12 pathologic Tc-99m perfusion… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 17 REFERENCES

Significance of nonuniform attenuation correction in quantitative brain SPECT imaging.

  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • 1998

SPECT imaging of normal subjects with technetium-99m-HMPAO and technetium-99m-ECD.

  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • 1997

Evaluation of SPECT scatter compensation methods by their effects on parameter estimation tasks,

S. C. Moore, M. F. Kijewski, S. P. Muller, T. R. Mcllvain, R. E. Zimmerman
  • J. Nucl. Med.
  • 1996

Nonstationary ‘resolution recovery for ROI activity estimation in SPECT,

S . C. Moore, M. F. Kijewski, S . P. Muller
  • J. Nucl. Med.,
  • 1996

ROI activity estimation with resolution recovery,

I M.F. Kijewski, S. P. Muller, S. C. Moore
  • J. Nucl. Med.,
  • 1995