Absolute Quantitation of Myocardial Blood Flow in Human Subjects With or Without Myocardial Ischemia Using Dynamic Flurpiridaz F 18 PET

  title={Absolute Quantitation of Myocardial Blood Flow in Human Subjects With or Without Myocardial Ischemia Using Dynamic Flurpiridaz F 18 PET},
  author={R. Packard and S. Huang and M. Dahlbom and J. Czernin and J. Maddahi},
  journal={The Journal of Nuclear Medicine},
  pages={1438 - 1444}
  • R. Packard, S. Huang, +2 authors J. Maddahi
  • Published 2014
  • Medicine
  • The Journal of Nuclear Medicine
  • Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of analyzing coronary artery disease (CAD) but subject to the various shortcomings of available radiotracers. Flurpiridaz F 18 is a novel PET radiotracer that exhibits properties of an ideal tracer. Methods: A new absolute perfusion quantitation method with flurpiridaz was developed, taking advantage of the early kinetics and high first-pass extraction by the myocardium of this radiotracer, and the first-in… CONTINUE READING
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