Absolute Quantitation of Myocardial Blood Flow in Human Subjects With or Without Myocardial Ischemia Using Dynamic Flurpiridaz F 18 PET
@article{Packard2014AbsoluteQO, title={Absolute Quantitation of Myocardial Blood Flow in Human Subjects With or Without Myocardial Ischemia Using Dynamic Flurpiridaz F 18 PET}, author={R. Packard and S. Huang and M. Dahlbom and J. Czernin and J. Maddahi}, journal={The Journal of Nuclear Medicine}, year={2014}, volume={55}, pages={1438 - 1444} }
Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of analyzing coronary artery disease (CAD) but subject to the various shortcomings of available radiotracers. Flurpiridaz F 18 is a novel PET radiotracer that exhibits properties of an ideal tracer. Methods: A new absolute perfusion quantitation method with flurpiridaz was developed, taking advantage of the early kinetics and high first-pass extraction by the myocardium of this radiotracer, and the first-in… CONTINUE READING
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References
SHOWING 1-10 OF 25 REFERENCES
Simplified Quantification of Myocardial Flow Reserve with flurpiridaz F 18: Validation with Microspheres in a Pig Model
- Chemistry, Medicine
- The Journal of Nuclear Medicine
- 2011
- 62
- PDF
Diagnostic value of PET-measured heterogeneity in myocardial blood flows during cold pressor testing for the identification of coronary vasomotor dysfunction
- Medicine
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
- 2007
- 21
- PDF
Cardiac PET imaging for the detection and monitoring of coronary artery disease and microvascular health.
- Medicine
- JACC. Cardiovascular imaging
- 2010
- 292
- Highly Influential
Prediction of Short-Term Cardiovascular Events Using Quantification of Global Myocardial Flow Reserve in Patients Referred for Clinical 82Rb PET Perfusion Imaging
- Medicine
- The Journal of Nuclear Medicine
- 2011
- 178
- PDF
Reproducibility of measurements of regional resting and hyperemic myocardial blood flow assessed with PET.
- Chemistry, Medicine
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine
- 1996
- 140
Potential utility of rubidium 82 pet quantification in patients with 3-vessel coronary artery disease
- Medicine
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
- 2004
- 243
Influence of Age and Hemodynamics on Myocardial Blood Flow and Flow Reserve
- Medicine
- Circulation
- 1993
- 457
Initial Characterization of an 18F-Labeled Myocardial Perfusion Tracer
- Medicine, Chemistry
- Journal of Nuclear Medicine
- 2008
- 129
- Highly Influential
- PDF
Evaluation of a Novel 18F-Labeled Positron-Emission Tomography Perfusion Tracer for the Assessment of Myocardial Infarct Size in Rats
- Medicine
- Circulation. Cardiovascular imaging
- 2009
- 54
- PDF