Absence of viral envelope proteins in equine herpesvirus 1-infected blood mononuclear cells during cell-associated viremia.

@article{Meulen2006AbsenceOV,
  title={Absence of viral envelope proteins in equine herpesvirus 1-infected blood mononuclear cells during cell-associated viremia.},
  author={Karen M van der Meulen and Brigitte Caij and Maurice B Pensaert and Hans Nauwynck},
  journal={Veterinary microbiology},
  year={2006},
  volume={113 3-4},
  pages={265-73}
}
In vitro studies demonstrated that most equine herpesvirus 1 (EHV-1)-infected peripheral blood mononuclear cells (PBMC) do not expose viral envelope proteins on their surface. This protects them against antibody-dependent lysis. We examined whether viral envelope proteins are also undetectable on infected PBMC during cell-associated viremia. Further, surface expression of major histocompatibility complex (MHC)-I was examined, since MHC-I assists in making infected cells recognizable for… CONTINUE READING

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