Absence of the hemochromatosis gene Cys282Tyr mutation in three ethnic groups from Algeria (Mzab), Ethiopia, and Senegal

@article{Roth1997AbsenceOT,
  title={Absence of the hemochromatosis gene Cys282Tyr mutation in three ethnic groups from Algeria (Mzab), Ethiopia, and Senegal},
  author={M E Roth and Pilar Giraldo and Ghania Hariti and Estella S. Poloni and Alicia Sanchez-Mazas and Gian Franco de Stefano and Jean Michel Dugoujon and Helene L. Coppin},
  journal={Immunogenetics},
  year={1997},
  volume={46},
  pages={222-225}
}
 A Celtic origin for hemochromatosis, a common genetic iron metabolism disorder, has been postulated for a long time. To check whether the two mutations recently identified in the HLA-class I candidate gene for this disease were found only in Caucasians, we examined their frequencies in individuals originating from Algeria, Ethiopia, and Senegal. The… CONTINUE READING