Absence of the hemochromatosis gene Cys282Tyr mutation in three ethnic groups from Algeria (Mzab), Ethiopia, and Senegal

@article{Roth1997AbsenceOT,
  title={Absence of the hemochromatosis gene Cys282Tyr mutation in three ethnic groups from Algeria (Mzab), Ethiopia, and Senegal},
  author={M.-P. Roth and P. Giraldo and G. Hariti and E. Poloni and A. Sanchez-Mazas and G. F. Stefano and Jean-Michel Dugoujon and H. Coppin},
  journal={Immunogenetics},
  year={1997},
  volume={46},
  pages={222-225}
}
  • M.-P. Roth, P. Giraldo, +5 authors H. Coppin
  • Published 1997
  • Biology, Medicine
  • Immunogenetics
  • Abstract A Celtic origin for hemochromatosis, a common genetic iron metabolism disorder, has been postulated for a long time. To check whether the two mutations recently identified in the HLA-class I candidate gene for this disease were found only in Caucasians, we examined their frequencies in individuals originating from Algeria, Ethiopia, and Senegal. The presumably disease-causing mutation, responsible for the Cys282Tyr substitution, was not found in any member of these ethnic groups… CONTINUE READING

    Tables and Topics from this paper.

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 19 REFERENCES
    Haemochromatosis and HLA–H
    244
    Mutation analysis in hereditary hemochromatosis.
    308