Absence of profound hyperinsulinism in polycystic ovary syndrome is associated with subtle elevations in the plasminogen activator inhibitor system.

@article{Sills2003AbsenceOP,
  title={Absence of profound hyperinsulinism in polycystic ovary syndrome is associated with subtle elevations in the plasminogen activator inhibitor system.},
  author={E Scott Sills and Carolyn D Drews and Mark Perloe and Michael J. Tucker and Carolyn R. Kaplan and Gianpiero D. Palermo},
  journal={Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology},
  year={2003},
  volume={17 3},
  pages={231-7}
}
In order to describe potential hypofibrinolytic tendencies in young (< 35 years) polycystic ovary syndrome (PCOS) patients, we studied plasminogen activator inhibitor (PAI-1) system components in women without laboratory evidence of hyperinsulinism or hyperandrogenism. The study was a prospective, observational comparison and took place in a major urban infertility referral center. Age, body mass index, ovulatory status, selected androgen levels, fasting insulin and plasma lipids were measured… CONTINUE READING

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