Absence of over-expression of p53 protein in benign and malignant paragangliomas.

@article{Wolfe1994AbsenceOO,
  title={Absence of over-expression of p53 protein in benign and malignant paragangliomas.},
  author={Ken Wolfe and John R. Gosney and Carol Beesley},
  journal={Oncology reports},
  year={1994},
  volume={1 6},
  pages={1219-21}
}
Expression of abnormally stable mutant forms of the protein encoded by the gene known as p53 is an extremely common event in human neoplasms, a fact reflecting its crucial role in the regulation of cell turnover. Although widely investigated in a range of tumours from a variety of sites, there do not, to our knowledge, appear to have been any studies of its expression in paragangliomas. Abnormal expression of p53 protein was absent from 15 morphologically typical adrenal (2) and extra-adrenal… CONTINUE READING

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