Absence of mutations in GJB2 (Connexin-26) gene in an ethnic group of southwest Iran

@inproceedings{Galehdari2009AbsenceOM,
  title={Absence of mutations in GJB2 (Connexin-26) gene in an ethnic group of southwest Iran},
  author={Hamid Galehdari and Ali Mohammad Foroughmand and Maryam Naderi Soorki and Gholamreza Mohammadian},
  booktitle={Indian journal of human genetics},
  year={2009}
}
BACKGROUND The common GJB2 gene mutation (35delG) has been previously reported from Iranian patients that were affected with nonsyndromic autosomal recessive deafness. We, therefore, for the first time, investigated the prevalence and frequency of the GJB2 gene mutation in the Iranian deaf population with Arabian origins. MATERIALS AND METHODS We amplified and sequenced the entire coding sequence of the GJB2 gene from 61 deaf patients and 26 control subjects. RESULT None of the analyzed… CONTINUE READING

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