Absence of mutagenic effects of sodium dichloroacetate.


Sodium dichloroacetate (DCA) is a drug with potential for treating patients with stroke and head injury. Conflicting evidence has been published on the mutagenic potential of DCA. A series of genetic tests for mutagenicity and clastogenicity was carried out on pharmaceutical grade DCA. Four types of mutagenicity test were included, with and without… (More)


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@article{Fox1996AbsenceOM, title={Absence of mutagenic effects of sodium dichloroacetate.}, author={Anthony W. Fox and X Yang and Hemalatha Murli and Timothy E Lawlor and Maria A. Cifone and Frederick E. Reno}, journal={Fundamental and applied toxicology : official journal of the Society of Toxicology}, year={1996}, volume={32 1}, pages={87-95} }