Absence of intravitreal bevacizumab-induced neuronal toxicity in the retina.

@article{Kim2008AbsenceOI,
  title={Absence of intravitreal bevacizumab-induced neuronal toxicity in the retina.},
  author={Jin Hyoung Kim and Cinoo Kim and Byung Ju Lee and Young Suk Yu and Kyu Hyung Park and Kyu-Won Kim},
  journal={Neurotoxicology},
  year={2008},
  volume={29 6},
  pages={1131-5}
}
Bevacizumab is a complete humanized monoclonal antibody directed against all isoforms of vascular endothelial growth factor (VEGF). It was originally used as a first-line treatment for metastatic colorectal cancer. Recently, intravitreal bevacizumab has been effectively applied to vasoproliferative diseases, such as retinal and choroidal neovascularization. However, it is known that intravenous administration of bevacizumab in the treatment of cancer can lead to serious adverse events, such as… CONTINUE READING

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