Absence of in vitro or in vivo bystander effects in a thymidine kinase-transduced murine T lymphoma

@article{Rivas2000AbsenceOI,
  title={Absence of in vitro or in vivo bystander effects in a thymidine kinase-transduced murine T lymphoma},
  author={Carmen Navarro Rivas and P. R. Chandler and Junia V. Melo and Elizabeth Simpson and Jane F Apperley},
  journal={Cancer Gene Therapy},
  year={2000},
  volume={7},
  pages={954-962}
}
Among the goals of an optimal gene transfer system are a predictably high efficiency of transfer and the ability to confer stable gene expression. An additional benefit of strategies designed to target tumor or effector cells could be the induction of a bystander effect. Although tumor killing by the bystander effect in vivo has been obtained in several types of malignant tumors, it has not been reported for T lymphomas. The goals of this work were to determine the stability of the expression… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Mechanism of RIVAS, CHANDLER, MELO, ET AL: LACK OF A BYSTANDER EFFECT IN TK1 MURINE T-LYMPHOMA CELLS

H Ishiimorita, R Agbaria, CA Mullen
  • Cancer Gene Therapy,
  • 2000

Suicide therapy of chemically induced mammary tumor in rat: efficacy and distant bystander effect

XW Ming, P Bougnoux, B Sacre-Salem
  • Cancer Res
  • 1998
VIEW 1 EXCERPT

The immunogenicity of experimental tumors is strongly biased by the expression of dominant viral cytotoxic T-lymphocyte epitopes

G Iezi, L Rivolta, A Ronchetti
  • Cancer Res
  • 1997
VIEW 1 EXCERPT