Absence of disease related prion protein in neurodegenerative disorders presenting with Parkinson's syndrome.

@article{Jendroska1994AbsenceOD,
  title={Absence of disease related prion protein in neurodegenerative disorders presenting with Parkinson's syndrome.},
  author={K Jendroska and O Hoffmann and L Schelosky and A J Lees and W Poewe and S E Daniel},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1994},
  volume={57 10},
  pages={1249-51}
}
  • K Jendroska, O Hoffmann, +3 authors S E Daniel
  • Published 1994 in
    Journal of neurology, neurosurgery, and…
Movement disorders presenting with parkinsonism may share histopathological features with Creutzfeldt-Jakob disease, a spongiform encephalopathy caused by the accumulation of pathological prion protein in brain. To investigate a possible aetiological link between these conditions and Creutzfeldt-Jakob disease, histoblot immunostaining for pathological prion protein was carried out in 90 cases including idiopathic Parkinson's disease, multiple system atrophy, diffuse Lewy body disease, Steele… CONTINUE READING