Absence of correlation between radiation-induced CD8 T-lymphocyte apoptosis and sequelae in patients with prostate cancer accidentally overexposed to radiation

@inproceedings{Vogin2018AbsenceOC,
  title={Absence of correlation between radiation-induced CD8 T-lymphocyte apoptosis and sequelae in patients with prostate cancer accidentally overexposed to radiation},
  author={Guillaume Vogin and J L Merlin and Alexandra Rousseau and Didier Peiffert and Alexandre Harl{\'e} and Marie Husson and Labib El Hajj and Mihai Levitchi and Tabassome Simon and J. M. Torres Sim{\'o}n},
  booktitle={Oncotarget},
  year={2018}
}
Purpose 454 patients with prostate adenocarcinoma were accidentally overexposed to radiation in Epinal hospital, France, between August 1999 and January 2007. We aimed toevaluate whether radiation-induced CD4 or CD8 T-lymphocyte apoptosis (RILA) correlates with the severity of radiation toxicity. Methods Between 2007 and 2013, all patients who received more than 108% of the prescribed radiation dose, after correction of the treatment plan, were convened, and blood was sampled at 6-months… CONTINUE READING

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