Absence of correlation between T-lymphocyte activity and development of carcinogen-induced skin tumor in mice.


Splenic lymphocytes obtained from female ICR/JCL mice, which had received combined radiation and chemical treatment for induction of skin tumors on their back skin, were tested for their ability to undergo proliferative response to non-specific mitogens as well as to allogeneic lymphocytes in vitro during 18 months after carcinogenic treatment. The treated… (More)


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