Absence of cognitive impairment or decline in preclinical Alzheimer's disease.

@article{Goldman2001AbsenceOC,
  title={Absence of cognitive impairment or decline in preclinical Alzheimer's disease.},
  author={William P Goldman and Joseph L. Price and Martha Storandt and Elizabeth A. Grant and D Mckeel and Eugene H. Rubin and John C. Morris},
  journal={Neurology},
  year={2001},
  volume={56 3},
  pages={361-7}
}
OBJECTIVE To determine whether clinically nondemented elderly individuals with pathologically confirmed preclinical AD are characterized by cognitive decline as measured by psychometric tests before death. METHODS Psychometric performance was examined retrospectively in 14 individuals who were nondemented at time of death and grouped in accordance with their neuropathologic findings: 1) Healthy brain (n = 9) was characterized by the absence of senile plaques or by only patchy neocortical… CONTINUE READING

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