Absence of c4d deposition in human composite tissue (hands and face) allograft biopsies: an immunoperoxidase study.

@article{Kanitakis2007AbsenceOC,
  title={Absence of c4d deposition in human composite tissue (hands and face) allograft biopsies: an immunoperoxidase study.},
  author={Jean Kanitakis and Brigitte McGregor and Lionel Badet and Palmina P. Petruzzo and E. Morelon and Bernard Devauchelle and Jean Michel Dubernard},
  journal={Transplantation},
  year={2007},
  volume={84 2},
  pages={265-7}
}
Deposition of the C4d complement degradation product has been shown to be a marker of antibody-mediated rejection of solid organ allografts, including kidney, heart, liver, and lung. We investigated whether C4d deposition also would be useful in monitoring rejection in human composite tissue allografts. A total of 60 mucocutaneous formalin-fixed, paraffin-embedded and four frozen biopsy specimens from four patients with composite tissue allografts (three hands, one face) taken during a period… CONTINUE READING
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