Absence of blocking effect of quinidine on responses to norepinephrine in the isolated dog atrium.

@article{Chiba1976AbsenceOB,
  title={Absence of blocking effect of quinidine on responses to norepinephrine in the isolated dog atrium.},
  author={Shigetoshi Chiba},
  journal={Japanese heart journal},
  year={1976},
  volume={17 4},
  pages={506-11}
}
The isolated right dog atrium was perfused through the sinus node artery with blood led from a heparinized support dog under constant perfusion pressure of 100 mmHg. The positive chronotropic and inotropic responses to norepinephrine were not significantly suppressed by treatment with large amounts of quinidine or procainamide, but completely blocked by… CONTINUE READING