Absence of association between a polymorphic GGC repeat in the 5′ untranslated region of the reelin gene and autism

@article{Krebs2002AbsenceOA,
  title={Absence of association between a polymorphic GGC repeat in the 5′ untranslated region of the reelin gene and autism},
  author={M O Krebs and Catalina Betancur and Sophie Leroy and Marie Chantal Bourdel and Christopher Gillberg and Marion Leboyer},
  journal={Molecular Psychiatry},
  year={2002},
  volume={7},
  pages={801-804}
}
Autism is a complex neurodevelopmental disorder with severe cognitive and communication disabilities, that has a strong genetic predisposition.1 Reelin, a protein involved in neuronal migration during development, is encoded by a gene located on 7q22,2 within the candidate region on 7q showing increased allele sharing in previous genome scans.3–8 A case/control and family-based association study recently reported a positive association between a trinucleotide repeat polymorphism (GGC) located… CONTINUE READING

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A genomewide screen for autism : strong evidence for linkage to chromosomes 2 q , 7 q , and 16 p

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