Absence of arsenite mutagenicity in E coli and Chinese hamster cells.

  title={Absence of arsenite mutagenicity in E coli and Chinese hamster cells.},
  author={T. Rossman and David Stone and Mar{\'i}a Molina and Walter Troll},
  journal={Environmental mutagenesis},
  volume={2 3},
Because exposure to compounds of arsenic has been implicated as a cause of cancer, an investigation of the mutagenicity of sodium aresenite in E coli and in Chinese hamster cells was performed. In the E coli system, Trp + revertants were not induced by arsenite in a variety of experimental protocols including spot tests, treat and plate protocols, and fluctuation tests. The mutator effect of a tif-1 strain was partially blocked by arsenite. Arsenite did not cause the induction of lambda… CONTINUE READING

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