Absence of an association between past infection with hepatitis A virus and primary hepatocellular carcinoma.

@article{Tabor1980AbsenceOA,
  title={Absence of an association between past infection with hepatitis A virus and primary hepatocellular carcinoma.},
  author={Edward Tabor and Dimitrios Trichopoulos and Orestes N Manousos and Xenophon Zavitsanos and JacquesA. Drucker and RobertJ. Gerety},
  journal={International journal of epidemiology},
  year={1980},
  volume={9 3},
  pages={
          221-3
        }
}
Serum samples from 77 caucasians of Greek origin with primary hepatocellular carcinoma (PHC) and 77 age- and sex-matched controls were tested for antibody to the hepatitis A virus (anti-HAV). Anti-HAV was detected in 63 patients with PHC (82%) and in 70 controls (91%). These data suggest that past infection with hepatitis A virus is not related to the development of PHC, in marked contrast to the strong association between PHC and HBV.