Absence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic models.

Abstract

OBJECTIVE Chronic asthma is characterized by ongoing recruitment of inflammatory cells and airway hyperresponsiveness leading to structural airway remodeling. Although alpha 4 beta 1 and beta2 integrins regulate leukocyte migration in inflammatory diseases and play decisive roles in acute asthma, their role has not been explored under the chronic asthma… (More)
DOI: 10.1016/j.exphem.2009.03.010

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Cite this paper

@article{Banerjee2009AbsenceOA, title={Absence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic models.}, author={Ena Ray Banerjee and Yi Jiang and William Reed Henderson and Yvette E. Latchman and Thalia Papayannopoulou}, journal={Experimental hematology}, year={2009}, volume={37 6}, pages={715-727.e3} }