Absence of albumin receptor on brain capillaries in vivo or in vitro.

@article{Pardridge1985AbsenceOA,
  title={Absence of albumin receptor on brain capillaries in vivo or in vitro.},
  author={William M Pardridge and J B Eisenberg and William T. Cefalu},
  journal={The American journal of physiology},
  year={1985},
  volume={249 3 Pt 1},
  pages={E264-7}
}
Hormones and drugs are known to be available for transport into brain and liver in vivo from the circulating albumin-bound pool. An albumin receptor-mediated mechanism is one possible way in which the transport of ligands from the circulating albumin-bound pool into the tissue may be catalyzed. The albumin receptor model was tested for brain in the present studies using both 125I-albumin (labeled by lactoperoxidase) and [3H]albumin (labeled by reductive methylation). The interaction of the… CONTINUE READING