Absence of a cumulative deterioration of regional function during three repeated 5 or 15 minute coronary occlusions.


Recurrent myocardial ischemia is commonly seen in patients with coronary artery disease, in patients undergoing cardiac surgery with intermittent cross-clamping, and experimentally when multiple occlusion preparations are used to test drugs. Our study was designated to investigate whether myocardial injury is cumulative after three sequential ischemic… (More)


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