Absence of Vascular Injury with Change in Dilution Rate for I.V. Injection of Antimicrobial Drugs into Rabbit Pinna Vein

@article{Ooi2006AbsenceOV,
  title={Absence of Vascular Injury with Change in Dilution Rate for I.V. Injection of Antimicrobial Drugs into Rabbit Pinna Vein},
  author={K. Ooi and J. Arai and Hiroyuki Kimizuka and H. Ueda and Y. Morimoto},
  journal={Japanese Journal of Pharmaceutical Health Care and Sciences},
  year={2006},
  volume={32},
  pages={710-713}
}
  • K. Ooi, J. Arai, +2 authors Y. Morimoto
  • Published 2006
  • Medicine
  • Japanese Journal of Pharmaceutical Health Care and Sciences
We continuously injected 9 antimicrobial drugs (Viccillin®, Pentcillin®, Unasyn-S®, Pansporin®, Cefmetazon®, Rocephin®, Sulperazon®, Flumarin®, Fosmicin-S®) intravenously into the rabbit pinna vein. For the dissolution of the drugs, we used a 0.9% isotonic sodium chloride as the physiological saline solution in a volume of either 50 mL or 100 mL. We conducted pathological examinations consisting of number of white blood cells (WBC), production of the C-reactive protein (CRP) and vascular lesion… Expand