Absence of PPP2R1A mutations in Wilms tumor

  title={Absence of PPP2R1A mutations in Wilms tumor},
  author={E. Cristy Ruteshouser and Linda K. Ashworth and Vicki Huff},
Evidence from genetic linkage analysis indicates that a gene located at 19q13.4, FWT2, is responsible for predisposition to Wilms tumor in many Wilms tumor families. This region has also been implicated in the etiology of sporadic Wilms tumor through loss of heterozygosity analyses. The PPP2R1A gene, encoding the α isoform of the heterotrimeric serine… CONTINUE READING