Absence of H186R polymorphism in exon 4 of the APOBEC3G gene among North Indian individuals.

Abstract

AIDS restriction genes have been defined in which allelic variations have been shown to influence infection or disease progression. Members of the APOBEC family of cellular polynucleotide cytidine deaminases (e.g., APOBEC3G) have been identified as a host factor that inhibits HIV-1 replication. It deaminates cytidine to uridine in nascent minus-strand viral… (More)
DOI: 10.1089/gte.2008.0017

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