Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice.


BACKGROUND Serotonin (5-HT) plays a complex regulatory role in processes like anxiety, depression, aggression, and impulse control. Due to the large amount of serotonergic receptors, knockout mice offer an important opportunity to investigate the role of specific receptors. The 5-HT(1B) receptor is thought to mediate aggression and impulse control. This was… (More)


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