Absence of  “Original Antigenic Sin” in Autoimmunity Provides an Unforeseen Platform for Immune Therapy

Abstract

I n this issue of The Journal of Experimental Medicine , Tuohy et al. study the spreading of the autoimmune response to myelin antigens in experimental autoimmune encephalo-myelitis (EAE) and its likely human counterpart, multiple sclerosis (MS) (1). They demonstrate that as disease develops in EAE and MS, reactivity to the initiating antigen diminishes… (More)

Topics

1 Figure or Table

Slides referencing similar topics