Abolition of magnesium chelatase activity by the gun5 mutation and reversal by Gun4.

@article{Davison2011AbolitionOM,
  title={Abolition of magnesium chelatase activity by the gun5 mutation and reversal by Gun4.},
  author={Paul A. Davison and C. Neil Hunter},
  journal={FEBS letters},
  year={2011},
  volume={585 1},
  pages={183-6}
}
The chlorophyll-deficient gun5-1 and cch Arabidopsis mutants carry single point mutations in the CHLH subunit of the magnesium chelatase enzyme, which catalyses the first committed step of chlorophyll biosynthesis. Recombinant Synechocystis ChlH subunits carrying the gun5-1 or cch mutations are inactive in Mg-chelatase assays, despite being able to bind both substrate and product, and retaining a capacity to form a ChlH-ChlI-ChlD Mg-chelatase complex. These mutant subunits act as inhibitors of… CONTINUE READING

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