AbobotulinumtoxinA: A Review in Pediatric Lower Limb Spasticity
@article{Syed2017AbobotulinumtoxinAAR, title={AbobotulinumtoxinA: A Review in Pediatric Lower Limb Spasticity}, author={Yahiya Y. Syed}, journal={Pediatric Drugs}, year={2017}, volume={19}, pages={367-373} }
AbobotulinumtoxinA (Dysport®) is currently the only botulinum toxin A formulation approved by the US FDA for the treatment of lower limb spasticity in pediatric patients aged ≥2 years. Intramuscular abobotulinumtoxinA was approved based on the results of a pivotal phase 3 trial in children with lower limb spasticity due to cerebral palsy. In this trial, a single treatment cycle with abobotulinumtoxinA 10–15 U/kg/leg injected into the gastrocnemius and soleus muscles significantly improved ankle… CONTINUE READING
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