Abnormalities of the photoreceptor-bipolar cell synapse in a substrain of C57BL/10 mice.

@article{Ruether2000AbnormalitiesOT,
  title={Abnormalities of the photoreceptor-bipolar cell synapse in a substrain of C57BL/10 mice.},
  author={Klaus Ruether and Jocelyn Grosse and Eike T Matthiessen and Katrin Hoffmann and Christian Hartmann},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 12},
  pages={4039-47}
}
PURPOSE A preferential loss of ERG b-wave was detected in a substrain of C57BL/10 mice. Electroretinographic and histologic techniques were used to investigate this hitherto unknown retinopathy. METHODS ERGs were obtained from normal and affected C57BL/10. C57BL/6 mice served also as controls. a-Wave and c-wave analyses were performed. Microscopic investigations were done at two different ages. RESULTS In the scotopic ERG, a severe reduction of the b-wave amplitude could be observed… CONTINUE READING
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