Abnormalities of the FHIT gene in human oral carcinogenesis


The abnormalities of the fragile histidine triad (FHIT) gene in tissue samples of oral squamous cell carcinomas (SCCs) along with several leukoplakias and an erythroplakia were examined to determine whether the FHIT gene is actually a frequent target in vivo for alteration during oral carcinogenesis. Abnormal transcripts of the FHIT gene were found in eight… (More)
DOI: 10.1054/bjoc.1999.1009


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@article{Tanimoto2000AbnormalitiesOT, title={Abnormalities of the FHIT gene in human oral carcinogenesis}, author={Kousuke Tanimoto and S. Hayashi and Eiko Tsuchiya and Yoshio Tokuchi and Y. Kobayashi and Koji Yoshiga and Tatsuo Okui and M. Kobayashi and T. Ichikawa}, journal={British Journal of Cancer}, year={2000}, volume={82}, pages={838 - 843} }