Abnormalities of smooth pursuit and saccadic control in schizophrenia and affective disorders

@article{Abel1992AbnormalitiesOS,
  title={Abnormalities of smooth pursuit and saccadic control in schizophrenia and affective disorders},
  author={Larry A. Abel and Smadar Levin and Philip S. Holzman},
  journal={Vision Research},
  year={1992},
  volume={32},
  pages={1009-1014}
}

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The reaction time results are unlikely to be an effect of treatment with antipsychotic medication and are inconsistent with the hypothesis that schizophrenia patients have frontal eye field pathology.

Saccadic eye movements in schizophrenic patients

Smooth pursuit performance in patients with affective disorders or schizophrenia and normal controls: analysis with specific oculomotor measures, RMS error and qualitative ratings

Data indicate two smooth pursuit performance deficits in schizophrenia: patients spend less time engaged in scoreable smooth pursuit and have low gain (accompanied by increased compensatory saccades) when the smooth pursuit is engaged.

Mixture analysis of smooth pursuit eye movements in schizophrenia.

Findings indicating that the eye movement data of schizophrenic patients is best represented by the mixture of two groups, one of which has distinctly poor performance are replicated and extended.

Comparison of the smooth eye tracking disorder of schizophrenics with that of nonhuman primates with specific brain lesions.

The ETD following lesions of the frontal lobe is unique in that it closely resembles the ETD of schizophrenics and lends further support for frontal lobe theories of schizophrenia.

Target anticipation and impairment of smooth pursuit eye movements in schizophrenia

Abstract A reduced gain of smooth pursuit eye velocity has frequently been reported in schizophrenic patients. With respect to predictable stimuli, this could be due to a deficit in predicting the

Eye tracking dysfunction in schizophrenia: characterization and pathophysiology.

The evidence suggests that ETD involves higher-order structures, including the frontal eye fields, which adjust the gain of the pursuit response to visual and anticipated target movement, as well as early parts ofThe pursuit pathway, including motion areas (the middle temporal area and the adjacent medial superior temporal area).

Smooth pursuit and antisaccade eye movements as endophenotypes in schizophrenia spectrum research.

The results generally confirmed the validity of the SPEM and antisaccade deficits as schizophrenia spectrum endophenotypes: Oculomotor performance was mostly stable both within and between assessments.
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