Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate.

@article{Moore2001AbnormalitiesOS,
  title={Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate.},
  author={Robert W. Moore and Thomas Rudy and T. M. Lin and Krzysztof Tomasz Ko and Richard Einer Peterson},
  journal={Environmental Health Perspectives},
  year={2001},
  volume={109},
  pages={229 - 237}
}
Several members of the phthalate ester family have antiandrogenic properties, yet little is known about how exposure to these ubiquitous environmental contaminants early in development may affect sexual development. We conducted experiments to determine effects of in utero and lactational exposure to the most prevalent phthalate ester, di(2-ethylhexyl) phthalate (DEHP), on male reproductive system development and sexual behavior. Sprague-Dawley rats were dosed with corn oil or DEHP (0, 375, 750… CONTINUE READING