Abnormalities of calcium cycling in the hypertrophied and failing heart.

Abstract

Progressive deterioration of cardiac contractility is a central feature of congestive heart failure (CHF) in humans. In this report we review those studies that have addressed the idea that alterations of intracellular calcium (Ca(2+)) regulation is primarily responsible for the depressed contractility of the failing heart. The review points out that Ca(2… (More)

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@article{Houser2000AbnormalitiesOC, title={Abnormalities of calcium cycling in the hypertrophied and failing heart.}, author={Steven R. Houser and Valentino Piacentino and Juliane Wei\sser}, journal={Journal of molecular and cellular cardiology}, year={2000}, volume={32 9}, pages={1595-607} }